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Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders.

机译：自身互补的腺相关病毒血清型6介导的aDamTs4敲低诱导退行性人髓核细胞中聚集蛋白聚糖的长期和有效增强：一种新的椎间盘疾病治疗方法。

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Demissew Shenegelegn Mern; Anja Tschugg; Sebastian Hartmann; Claudius Thomé;
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1. Identification and characterization of human nucleus pulposus cell specific serotypes of adeno-associated virus for gene therapeutic approaches of intervertebral disc disorders [J] . Demissew S Mern, Claudius Thomé BMC Musculoskeletal Disorders . 2015,第1期

机译：椎间盘疾病的基因治疗方法的腺相关病毒人髓核细胞特异性血清型的鉴定和表征
2. Hypoxia-inducible factor-1 alpha mediates aggrecan and collagen Pi expression via NOTCH1 signaling in nucleus pulposus cells during intervertebral disc degeneration [J] . Liu Zhuochao, Li Changwei, Meng Xiangchao, Biochemical and Biophysical Research Communications . 2017,第3期

机译：缺氧诱导因子-1α通过在椎间盘变性期间通过Nucleus purposus细胞中的Notch1信号传导介导骨髓和胶原Pi表达
3. Enhancing human nucleus pulposus cells for biological treatment approaches of degenerative intervertebral disc diseases: a systematic review [J] . Mern Demissew Shenegelegn, Beierfuss Anja, Thome Claudius, Journal of tissue engineering and regenerative medicine . 2014,第12期

机译：增强人髓核细胞用于退行性椎间盘疾病的生物治疗方法：系统综述
4. Stem Cell Seeded Biomimetic Nucleus Pulposus and Annulus Fibrosus Implants Promote Living Repair of Degenerative Intervertebral Discs in Sheep [C] . Borem R. M.S., Walters J. B.S., Madeline A., Society for Biomaterials annual meeting and exposition . 2018

机译：干细胞种子仿生核髓核和纤维环植入物促进绵羊变性椎间盘的生活修复。
5. Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders [O] . Demissew Shenegelegn Mern, Anja Tschugg, Sebastian Hartmann, -1

机译：自我补充腺相关病毒血清型6介导的ADAMTS4敲低诱导退化性人髓核细胞中聚集蛋白聚糖的长期和有效增强：椎间盘疾病的新治疗方法
6. Identification and characterization of human nucleus pulposus cell specific serotypes of adeno-associated virus for gene therapeutic approaches of intervertebral disc disorders [O] . 2015

机译：椎间盘疾病的基因治疗方法的人类核髓浆腺相关病毒血清型的鉴定和表征

Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders.

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